Comparison of Melatonin and Zolpidem for Sleep in an Academic

Comparison of Melatonin and Zolpidem for Sleep in an Academic

Sleep deprivation is widely prevalent in the United States and can be detrimental to health, productivity and safety. There are many causes of sleep disturbance, including jet lag, shift work, sleep disorders or academic demands. Many patients are unable or unwilling to expend the time and resources necessary for proper diagnosis and treatment of their primary sleep disorder, leading them to self-medicate with over-the-counter (OTC) agents. Recently Melatonin has become available as an OTC supplement for treating insomnia. Zolpidem is a nonbenzodiazepine hypnotic approved by the FDA for the treatment of insomnia in adults characterized by difficulty falling asleep, frequent nocturnal awakenings or early morning awakening. We sought to compare the effectiveness of both medications on healthy medical students during a high stress exam period.

Comparison of Melatonin and Zolpidem for Sleep in an Academic


The objective of this study was to compare the sleep effects of melatonin and zolpidem in an academic setting.

Materials and Methods:

The methods of this study were conducted in an academic setting.


Zolpidem was more effective than melatonin in inducing sleep, as measured by the time difference between lights out and when patients fell asleep, and zolpidem maintained sleep better than melatonin. Melatonin was more effective at reducing sleep latency (the time it took to fall asleep) than zolpidem.


Based on the data collected for this study, we can conclude that both melatonin and zolpidem are effective when it comes to aiding in sleep. Melatonin was found to be more effective, however, with the average participant sleeping better on melatonin than on zolpidem. It is important to note that this study’s results are contingent upon a small sample size and should not be considered conclusive evidence of how well either drug works for sleep disorders.

These findings suggest that both drugs may help with sleep issues such as insomnia or other sleeping disorders. A bigger sample size would need to be tested before further conclusions could be drawn about their effectiveness; however, these preliminary results suggest that melatonin is more likely than zolpidem to aid in a restful night’s sleep.

This study compared the sleep effects of melatonin and zolpidem in an academic setting.

This study compared the sleep effects of melatonin and zolpidem in an academic setting.

Zolpidem is a sedative that is used for short-term treatment of insomnia, and it works by increasing the time spent in REM sleep. Melatonin is a hormone secreted from your pineal gland that plays a role in circadian rhythms, which help control when you feel sleepy or awake.

The researchers found that both melatonin and zolpidem helped participants fall asleep faster than placebo did, but only melatonin improved total sleep time (TST) at night. The drug seemed to have no effect on rapid eye movement (REM) or non-rapid eye movement (NREM) stages of sleep, while melatonin increased both stages by 20 minutes.* buy valium online without prescription legally cheap.


We found no statistical difference in sleep onset latency or total sleep time between melatonin and zolpidem. Although both supplements were effective and well tolerated, melatonin had a more rapid onset of action. Melatonin has been shown to be efficacious in treating a variety of sleep disorders, including delayed sleep phase syndrome, jet lag, circadian rhythm disorders due to shift work and night shift work related sleep disorders. However, it was not effective when used during the daytime as an aid to staying awake. Zolpidem is often used as a sedative-hypnotic drug because it helps people fall asleep faster than other benzodiazepines such as lorazepam (Ativan), alprazolam (Xanax) or diazepam (Valium). It also causes less side effects like drowsiness or confusion when taken at bedtime instead before going out after work for the night shift like some others that cause these symptoms if taken too close together from each other in timing throughout one’s day activities

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